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My approach is a whole-food based ketogenic diet, that is high in fat, moderate in protein and very low in carbohydrates. The goal is to be in the state of therapeutical ketosis. 

It's important to eat only high quality whole foods to avoid dangerous additives and toxins. The elimination of certain plant groups, most importantly those that are high in oxalates (4), is crucial because of their harmful components. Adequate amount of protein is important to get enough essential amino acids and prevent malnutrition and sarcopenia. In this diet the necessary energy is provided by a fairly high amount of healthy fats. Drinking clean water and avoiding sweet drinks are also essential.

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The ketogenic diet has been shown to be effective in the case of ADPKD in animal (1) and human studies. In a randomized control trial there was an increase in estimated Glomerular Filtration Rate (eGFR) and a decrease in total kidney and liver volume in the ketogenic diet group compared to the water fasting and the standard kidney diet group. (3). This research is still new but extremely promising. 

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If you choose to work with me, during the 12-week program you will learn how to manage your disease with a diet that is based on the latest research. I offer nutrition coaching that includes one-on-one consultations via zoom, a one-week meal plan, recipe ideas and cooking tips as well as lifestyle advice to manage your exercise routine, stress and sleep. I will also help you to get a smooth transition phase into ketosis and give you diet related emotional support. 

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In case of ADPKD or DKD the best coaching option you'll find here. 

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Useful links & research ​

1. Ketosis Ameliorates Renal Cyst Growth in Polycystic Kidney Disease https://labs.mcdb.ucsb.edu/weimbs/thomas/sites/labs.mcdb.ucsb.edu.weimbs.thomas/files/biblio/files/2019cellmetabolism.pdf 

2. Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO- ADPKD—a randomized controlled trial https://www.cell.com/cell-reports-medicine/pdf/S2666-3791(23)00477-9.pdf

3. Ketogenic dietary interventions in autosomal dominant polycystic kidney disease-a retrospective case series study: first insights into feasibility, safety and effects https://pubmed.ncbi.nlm.nih.gov/35664270/

4. Crystal deposition triggers tubule dilation that accelerates cystogenesis in polycystic kidney diseasehttps://labs.mcdb.ucsb.edu/weimbs/thomas/sites/labs.mcdb.ucsb.edu.weimbs.thomas/files/biblio/files/2019jci.pdf

5. Salt, but not protein intake, is associated with accelerated disease progression in autosomal dominant polycystic kidney disease  https://www.kidney-international.org/article/S0085-2538(20)30636-0/pdf  

6. Factors influencing progression of renal failure in autosomal dominant polycystic kidney disease https://pubmed.ncbi.nlm.nih.gov/8749691/#:~:text 

7. PKD Guide, Steve Boswell https://docs.google.com/document/d/14hVT-455l63T5VSZH5fYS80pyvWAvCTQIqTmzIcMxug/edit?fbclid=IwAR0re7VE6MoMYQUNfB3jJqkQ02lgb0xy0bZYEIG7E-K1ctaTvuMjhvdr4NY

8. Virta’s Approach Improves Kidney Function, Offering Hope to Patients With Chronic Kidney Disease https://www.virtahealth.com/blog/virtas-approach-improves-kidney-function

9. Factors influencing progression of renal failure in autosomal dominant polycystic kidney disease https://pubmed.ncbi.nlm.nih.gov/8749691/#:~:text

10. https://santabarbaranutrients.com/ 

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